SCHEMBL14836770

SCHEMBL14836770

[O]C(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.56
PRMT1 Q99873 1/20 0.50
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
TSHR P16473 2/20 0.46
AKR1C3 P42330 1/20 0.46
ESR1 P03372 1/20 0.45
PLIN1 O60240 1/20 0.45
BCHE P06276 1/20 0.45
TNFRSF1A P19438 1/20 0.45
ACHE P22303 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL389392 0.79 AKR1C1 (0.54) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL368124 0.79 AKR1C1 (0.54) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL918848 0.79 AKR1C1 (0.54) AKR1C1PRMT1ALDH1A1LMNAMAPT
Bicarbonate SCHEMBL28922000 0.78 ESR1 (0.65) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL23069110 0.75 AKR1C1 (0.73) AKR1C1ALDH1A1LMNAMAPTMEN1
SCHEMBL3944037 0.75 AKR1C1 (0.55) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL27999897 0.75 AKR1C1 (0.73) AKR1C1ALDH1A1LMNAMAPTMEN1
SCHEMBL80025 0.74 AKR1C1 (0.74) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL55433 0.74 ESR1 (0.74) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL11167902 0.74 NFE2L2 (0.46) ALDH1A1LMNAMAPTMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103073440-B Diphenylvinyloxy alkylamine compound and preparation method as well as application thereof UNIV SICHUAN 2015-06-03 CN disclosed
CN-103073440-B Diphenylvinyloxy alkylamine compound and preparation method as well as application thereof UNIV SICHUAN 2015-06-03 CN disclosed
CN-103073440-A Diphenylvinyloxy alkylamine compound and preparation method as well as application thereof UNIV SICHUAN 2013-05-01 CN disclosed
CN-103073440-A Diphenylvinyloxy alkylamine compound and preparation method as well as application thereof UNIV SICHUAN 2013-05-01 CN disclosed
EP-2578565-A1 ALPHA-SUBSTITUTED ACRYLATE ESTERS, COMPOSITION CONTAINING SAME, AND METHOD FOR PRODUCING THE -SUBSTITUTED ACRYLATE ESTERS Nippon Shokubai Co., Ltd. (JP) 2013-04-10 EP disclosed