Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14833809 | 0.73 | CCKBR (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL14837218 | 0.65 | CHRNA7 (0.40) | CCR1SFRP1GAAMGLLCTSS | |
| SCHEMBL14815988 | 0.63 | KMT2A (0.46) | SFRP1MGLLKMT2A | |
| SCHEMBL4006938 | 0.61 | L3MBTL1 (0.39) | CTSSKMT2A | |
| SCHEMBL1222165 | 0.61 | ALDH1A1 (0.55) | GAAKMT2A | |
| SCHEMBL19640879 | 0.58 | KMT2A (0.56) | KMT2AHTR2CHTR6 | |
| SCHEMBL29500391 | 0.58 | KMT2A (0.56) | KMT2AHTR2CHTR6 | |
| Trifluoroacetic Acid SCHEMBL21819605 | 0.58 | SMN1; SMN2 (0.56) | KMT2A | |
| SCHEMBL4562704 | 0.58 | KMT2A (0.52) | KMT2AHTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL30150292 | 0.57 | KMT2A (0.79) | KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049174-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-A]PYRAZINE SULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | WO | disclosed |