Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003470 | 0.85 | CTSS (0.39) | CTSSSLC6A9SSTR4RXFP1EPHX2 | |
| SCHEMBL4292846 | 0.83 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL4005033 | 0.82 | EPHX2 (0.35) | KMT2ACTSSMEN1ALDH1A1EPHX2 | |
| SCHEMBL4001806 | 0.82 | ATM (0.44) | KMT2ACTSSALDH1A1CYP1A2EPHX2 | |
| SCHEMBL4006999 | 0.81 | EPHX2 (0.47) | L3MBTL1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL4009618 | 0.80 | PKM (0.40) | MAPTSLC6A2SLC6A4EPHX2 | |
| SCHEMBL4009421 | 0.80 | CNR1 (0.48) | L3MBTL1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL4010678 | 0.80 | HSD11B1 (0.45) | EPHX2 | |
| SCHEMBL4010564 | 0.79 | EPHX2 (0.35) | KMT2ASSTR4RXFP1MEN1ALDH1A1 | |
| SCHEMBL4006571 | 0.79 | HSD11B1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |