Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041835 | 0.88 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1SLC6A3 | |
| SCHEMBL12535764 | 0.87 | NCF1 (0.38) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL20041954 | 0.80 | NCF1 (0.33) | NCF1 | |
| SCHEMBL14431936 | 0.79 | NCF1 (0.35) | NCF1 | |
| SCHEMBL8504951 | 0.78 | — | — | |
| SCHEMBL6027356 | 0.77 | NCF1 (0.37) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL7513512 | 0.76 | — | — | |
| SCHEMBL16508783 | 0.75 | DRD2 (0.42) | GNAI3GNAO1GNAI1 | |
| SCHEMBL12535970 | 0.75 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL1689411 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049617-A1 | CRYSTALLINE FORMS OF A 3-[2-METHANESULFONYL-1-(4-TRIFLUOROMETHYL-PHENOXY)ETHYL]PYRROLIDINE COMPOUND | THERAVANCE, INC. (US) | 2013-04-04 | — | — | WO | disclosed |