SCHEMBL14838136

SCHEMBL14838136

CC(C)N(CC[C@H](c1ccccc1)c1cc(COC(=O)/C=C/C(=O)O)ccc1O)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 11/20 0.56
CHRM2 P08172 3/20 0.56
CHRM1 P11229 3/20 0.56
CHRM5 P08912 2/20 0.56
HRH1 P35367 2/20 0.56
LMNA P02545 1/20 0.56
ESR1 P03372 1/20 0.56
CHRM4 P08173 1/20 0.56
MAPT P10636 1/20 0.56
KCNE1 P15382 1/20 0.56
PTGS1 P23219 1/20 0.56
HRH2 P25021 1/20 0.56
HTR2A P28223 1/20 0.56
SLC6A4 P31645 1/20 0.56
ADRA1A P35348 1/20 0.56
OPRK1 P41145 1/20 0.56
KCNQ1 P51787 1/20 0.56
KCNH2 Q12809 1/20 0.56
CACNA1C Q13936 1/20 0.56
SCN5A Q14524 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17486754 0.91 CHRM3 (0.53) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL14696914 0.87 CHRM2 (0.56) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL14696913 0.87 CHRM2 (0.56) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL814972 0.87 CHRM2 (0.72) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL14709881 0.87 CHRM2 (0.72) CHRM3CHRM2CHRM1CHRM5HRH1
Desfesoterodine SCHEMBL14696972 0.86 CHRM2 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL2166483 0.86 CHRM2 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL8432689 0.86 CHRM3 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1
Fumaric Acid SCHEMBL19212481 0.86 CHRM3 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1
SCHEMBL9922432 0.86 CHRM2 (0.62) CHRM3CHRM2CHRM1CHRM5HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9751828-B2 Antimuscarinic compound having a low content of impurities DIPHARMA FRANCIS S.R.L. (IT) 2017-09-05 US disclosed
US-9751828-B2 Antimuscarinic compound having a low content of impurities DIPHARMA FRANCIS S.R.L. (IT) 2017-09-05 US disclosed
US-9440910-B2 Reference markers for fesoterodine fumarate ALEMBIC PHARMACEUTICALS LIMITED (IN) 2016-09-13 US disclosed
US-9440910-B2 Reference markers for fesoterodine fumarate ALEMBIC PHARMACEUTICALS LIMITED (IN) 2016-09-13 US disclosed
US-20160031796-A1 ANTIMUSCARINIC COMPOUND HAVING A LOW CONTENT OF IMPURITIES DIPHARMA FRANCIS S.R.L. (IT) 2016-02-04 US disclosed
US-20160031796-A1 ANTIMUSCARINIC COMPOUND HAVING A LOW CONTENT OF IMPURITIES DIPHARMA FRANCIS S.R.L. (IT) 2016-02-04 US disclosed
US-20150175526-A2 THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-06-25 US disclosed
US-20150175526-A2 THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-06-25 US disclosed
US-20140374284-A1 NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE ALEMBIC PHARMACEUTICALS LTD (IN) 2014-12-25 US disclosed
US-20140374284-A1 NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE ALEMBIC PHARMACEUTICALS LTD (IN) 2014-12-25 US disclosed
WO-2013046194-A2 THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2013-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140374284-A1 NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE SHBG, KLK3, FES CHRM3 268/4885CHRM2 230/4885CHRM1 928/4885
US-20160031796-A1 ANTIMUSCARINIC COMPOUND HAVING A LOW CONTENT OF IMPURITIES ADRA2B, ADRB2, ADRA1B CHRM3 4/4885CHRM2 9/4885CHRM1 60/4885
US-20150175526-A2 THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE SHBG, FES, KLK3 CHRM3 146/4885CHRM2 163/4885CHRM1 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.