SCHEMBL1484296

SCHEMBL1484296

C1COCOOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22534164 0.86 ALDH1A1 (0.47)
SCHEMBL8994603 0.84 ALDH1A1 (0.47)
SCHEMBL23883558 0.81 TSHR (0.46)
SCHEMBL12420634 0.81
Cyclooctane SCHEMBL1576491 0.79 TTR (0.33)
SCHEMBL3741249 0.78 ALDH1A1 (0.47)
SCHEMBL29967 0.77
Tetrahydrofuran SCHEMBL27299023 0.77 ALDH1A1 (0.67)
SCHEMBL1818620 0.76
Fluoride SCHEMBL29431535 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905344-B2 Propylene copolymer compositions suitable for foaming LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2024-02-20 US claimed
CN-112638955-B Propylene copolymer compositions suitable for foaming 鲁姆斯诺沃伦技术公司 2023-08-11 CN claimed
WO-2022134215-A1 THERMOSETTING RESIN COMPOSITION, RESIN ADHESIVE LIQUID CONTAINING SAME, PREPREG, LAMINATE, COPPER CLAD LAMINATE AND PRINTED CIRCUIT BOARD 广东生益科技股份有限公司 2022-06-30 WO claimed
EP-3802634-A1 PROPYLENE COPOLYMER COMPOSITIONS SUITABLE FOR FOAMING Lummus Novolen Technology Gmbh (DE) 2021-04-14 EP claimed
CN-112638955-A Propylene copolymer compositions suitable for foaming 鲁姆斯诺沃伦技术公司 2021-04-09 CN claimed
US-8334348-B2 Modification of polylactones such as polylactic acid with organic cyclic peroxides such as those known under tradename Trigonox 301, 3,6,9-triethyl-3,6,9-trimethyl-1,4,7-triperoxononane; results in a (co)polymer with a high degree of branching but free of gel formation; films, coatings and moldings AKZO NOBEL N.V. (NL) 2012-12-18 US claimed
EP-1991601-B1 PROCESS FOR THE MODIFICATION OF BIODEGRADABLE POLYMERS AKZO NOBEL NV (NL) 2010-08-25 EP claimed
US-20090124723-A1 PROCESS FOR THE MODIFICATION OF BIODEGRADABLE POLYMERS AKZO NOBEL N. V. (NL) 2009-05-14 US claimed
CN-1823053-A 1,2, 4-trioxepanes as lactone precursors AKZO NOBEL NV (NL) 2006-08-23 CN claimed
US-20060167281-A1 1,2,4- Trioxepanes as precursors for lactones AKZO NOBEL N.V. (NL) 2006-07-27 US claimed
EP-1646618-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES Akzo Nobel N.V. (NL) 2006-04-19 EP claimed
WO-2006016903-A2 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LABORATORIES, L.C. (US) 2006-02-16 WO claimed
US-20050256184-A1 1,2,4-Trioxanes and 1,2,4-trioxepanes O'NEILL PAUL M 2005-11-17 US claimed
WO-2005014569-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES AKZO NOBEL N.V. (NL) 2005-02-17 WO claimed
EP-0909269-B1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN CROMPTON CORP (US) 2005-02-09 EP claimed
EP-1309667-B1 USE OF TRIOXEPANS IN IGNITION IMPROVED FUELS AKZO NOBEL NV (NL) 2004-10-20 EP claimed
US-6540796-B2 Containing a trioxepin compound AKZO NOBEL N.V. (NL) 2003-04-01 US claimed
US-20020038524-A1 Use of trioxepans in ignition improved fuels AKZO NOBEL NV (NL) 2002-04-04 US claimed
US-5856412-A USING 1,2,4-TRIOXACYCLOHEPTANE WITCO CORPORATION (US) 1999-01-05 US claimed
JP-11106521-A None JP disclosed
US-20240400769-A1 METHOD FOR IMPROVING THE REACTIVE EXTRUSION OF A POLYPROPYLENE PCR BRASKEM S.A. (BR) 2024-12-05 US disclosed
US-11905344-B2 Propylene copolymer compositions suitable for foaming LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2024-02-20 US disclosed
US-20240002610-A1 SOLID-STATE METHOD FOR TREATING POLYAMIDE AND POLYESTER ARTICLES GREEN THEME TECHNOLOGIES, INC. 2024-01-04 US disclosed
US-11760847-B2 Solid-state method for treating polyamide and polyester articles GREEN THEME TECHNOLOGIES, INC. (US) 2023-09-19 US disclosed
CN-112638955-B Propylene copolymer compositions suitable for foaming 鲁姆斯诺沃伦技术公司 2023-08-11 CN disclosed
WO-2023146769-A1 SOLID-STATE METHOD FOR TREATING SYNTHETIC THERMOPLASTIC ARTICLES Green Theme Technologies Inc. (US) 2023-08-03 WO disclosed
US-20230235132-A1 SOLID-STATE METHOD FOR TREATING POLYAMIDE AND POLYESTER ARTICLES GREEN THEME TECHNOLOGIES, INC. 2023-07-27 US disclosed
CN-111902454-B Hyperbranched polylactide resin composition 自然工作有限责任公司 2023-05-30 CN disclosed
US-11566103-B2 Hyperbranched polylactide resin compositions NATURE WORKS LLC (US) 2023-01-31 US disclosed
EP-3746497-B1 HYPERBRANCHED POLYLACTIDE RESIN COMPOSITIONS NATUREWORKS LLC (US) 2022-03-23 EP disclosed
EP-3802634-A1 PROPYLENE COPOLYMER COMPOSITIONS SUITABLE FOR FOAMING Lummus Novolen Technology Gmbh (DE) 2021-04-14 EP disclosed
CN-112638955-A Propylene copolymer compositions suitable for foaming 鲁姆斯诺沃伦技术公司 2021-04-09 CN disclosed
EP-3746497-A1 HYPERBRANCHED POLYLACTIDE RESIN COMPOSITIONS NatureWorks LLC (US) 2020-12-09 EP disclosed
US-20200362102-A1 Hyperbranched Polylactide Resin Compositions NATUREWORKS, LLC 2020-11-19 US disclosed
CN-111902454-A Hyperbranched polylactide resin composition 自然工作有限责任公司 2020-11-06 CN disclosed
WO-2019152264-A1 HYPERBRANCHED POLYLACTIDE RESIN COMPOSITIONS NATUREWORKS LLC (US) 2019-08-08 WO disclosed
CN-105500855-A Multi-layer films comprising propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC 2016-04-20 CN disclosed
US-8334348-B2 Modification of polylactones such as polylactic acid with organic cyclic peroxides such as those known under tradename Trigonox 301, 3,6,9-triethyl-3,6,9-trimethyl-1,4,7-triperoxononane; results in a (co)polymer with a high degree of branching but free of gel formation; films, coatings and moldings AKZO NOBEL N.V. (NL) 2012-12-18 US disclosed
CN-101107297-B Process for preparing trioxepanes and their use for crosslinking polymers AKZO NOBEL NV 2012-11-21 CN disclosed
US-8232417-B1 Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals BIODERM RESEARCH (US) 2012-07-31 US disclosed
US-20120189567-A1 Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for Skin Imperfections and Infection in Mammals BIODERM RESEARCH (US) 2012-07-26 US disclosed
US-8193376-B2 Artemisinin derivatives with natural amino acids, peptides, and amino sugars for the treatment of infection and topical condition in mammals BIODERM RESEARCH (US) 2012-06-05 US disclosed
CN-101395199-B Process for the modification of biodegradable polymers Akzo Nobel Co.,Ltd. (NL) 2011-12-14 CN disclosed
EP-1828286-B1 PROCESS FOR PREPARING TRIOXEPANE COMPOSITION AND USE THEREOF IN CROSSLINKING POLYMERS AKZO NOBEL NV (NL) 2011-05-04 EP disclosed
CN-102015294-A Multilayer film containing propylene polymer EXXONMOBIL CHEM PATENTS INC 2011-04-13 CN disclosed
US-20110077193-A1 Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for the Treatment of Infection and Topical Condition in Mammals BIODERM RESEARCH (US) 2011-03-31 US disclosed
US-7825059-B2 Process for preparing trioxepane composition and use thereof in crosslinking polymers AKZO NOBEL N.V. (NL) 2010-11-02 US disclosed
EP-2240320-A2 MULTI-LAYER FILMS COMPRISING PROPYLENE-BASED POLYMERS ExxonMobil Chemical Patents Inc. (US) 2010-10-20 EP disclosed
EP-1991601-B1 PROCESS FOR THE MODIFICATION OF BIODEGRADABLE POLYMERS AKZO NOBEL NV (NL) 2010-08-25 EP disclosed
US-7713636-B2 Multi-layer films comprising propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-05-11 US disclosed
US-20090124723-A1 PROCESS FOR THE MODIFICATION OF BIODEGRADABLE POLYMERS AKZO NOBEL N. V. (NL) 2009-05-14 US disclosed
CN-101395199-A Process for the modification of biodegradable polymers AKZO NOBEL NV (NL) 2009-03-25 CN disclosed
WO-2008076535-A2 MULTI-LAYER FILMS COMPRISING PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-26 WO disclosed
US-20080145670-A1 Multi-layer films comprising propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. 2008-06-19 US disclosed
US-20080132651-A1 Process For Preparing Trioxepane Composition And Use Thereof In Crosslinking Polymers AKZO NOBEL N.V. (NL) 2008-06-05 US disclosed
CN-101107297-A Process for preparing trioxepanes and their use for crosslinking polymers AKZO NOBEL NV (NL) 2008-01-16 CN disclosed
US-20070269537-A1 Skin Condition Improvement Including Acne, Rosacea, and Topical Wounds by Artemisia Annua Extract via Iron Siderophore Trojan Horse Delivery System BIODERM RESEARCH (US) 2007-11-22 US disclosed
CN-1823053-A 1,2, 4-trioxepanes as lactone precursors AKZO NOBEL NV (NL) 2006-08-23 CN disclosed
CN-1823053-A 1,2, 4-trioxepanes as lactone precursors AKZO NOBEL NV (NL) 2006-08-23 CN disclosed
CN-1823053-A 1,2, 4-trioxepanes as lactone precursors AKZO NOBEL NV (NL) 2006-08-23 CN disclosed
US-20060167281-A1 1,2,4- Trioxepanes as precursors for lactones AKZO NOBEL N.V. (NL) 2006-07-27 US disclosed
US-20060167281-A1 1,2,4- Trioxepanes as precursors for lactones AKZO NOBEL N.V. (NL) 2006-07-27 US disclosed
US-20060167281-A1 1,2,4- Trioxepanes as precursors for lactones AKZO NOBEL N.V. (NL) 2006-07-27 US disclosed
WO-2006016903-A8 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LAB LC (US) 2006-07-20 WO disclosed
WO-2006016903-A3 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LAB LC (US) 2006-05-26 WO disclosed
EP-1646618-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES Akzo Nobel N.V. (NL) 2006-04-19 EP disclosed
EP-1646618-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES Akzo Nobel N.V. (NL) 2006-04-19 EP disclosed
WO-2006016903-A2 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LABORATORIES, L.C. (US) 2006-02-16 WO disclosed
WO-2006016903-A2 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LABORATORIES, L.C. (US) 2006-02-16 WO disclosed
US-20050256184-A1 1,2,4-Trioxanes and 1,2,4-trioxepanes O'NEILL PAUL M 2005-11-17 US disclosed
US-20050256184-A1 1,2,4-Trioxanes and 1,2,4-trioxepanes O'NEILL PAUL M 2005-11-17 US disclosed
US-20050256184-A1 1,2,4-Trioxanes and 1,2,4-trioxepanes O'NEILL PAUL M 2005-11-17 US disclosed
WO-2005014569-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES AKZO NOBEL N.V. (NL) 2005-02-17 WO disclosed
WO-2005014569-A1 1,2,4,-TRIOXEPANES AS PRECURSORS FOR LACTONES AKZO NOBEL N.V. (NL) 2005-02-17 WO disclosed
EP-0909269-B1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN CROMPTON CORP (US) 2005-02-09 EP disclosed
EP-0909269-B1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN CROMPTON CORP (US) 2005-02-09 EP disclosed
EP-1311556-B1 USE OF TRIOXEPANS IN THE PRODUCTION OF HIGH-SOLID ACRYLIC, STYRENIC AND LOW-DENSITY POLYETHYLENE TYPE RESINS AKZO NOBEL NV (NL) 2004-10-27 EP disclosed
EP-1309667-B1 USE OF TRIOXEPANS IN IGNITION IMPROVED FUELS AKZO NOBEL NV (NL) 2004-10-20 EP disclosed
US-6720398-B2 POLYMERIZATION OF MONOMER(S) INPRESENCE OF TRIOXEPAN COMPOUNDS AS INITIATOR AKZO NOBEL N.V. (NL) 2004-04-13 US disclosed
EP-1309584-B1 NOVEL TRIOXEPAN COMPOUNDS AKZO NOBEL NV (NL) 2004-04-07 EP disclosed
US-6566391-B2 Useful for degrading polypropylene AKZO NOBEL N.V. (NL) 2003-05-20 US disclosed
US-6540796-B2 Containing a trioxepin compound AKZO NOBEL N.V. (NL) 2003-04-01 US disclosed
EP-0909269-A4 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN CROMPTON CORP (US) 2002-08-14 EP disclosed
EP-0909269-A4 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN CROMPTON CORP (US) 2002-08-14 EP disclosed
US-20020052455-A1 Use of trioxepans in the process to make high-solid acrylic, styrenic, and LDPE-type resins AKZO NOBEL NV (NL) 2002-05-02 US disclosed
US-20020040152-A1 Novel trioxepan compounds AKZO NOBEL NV (NL) 2002-04-04 US disclosed
US-20020038524-A1 Use of trioxepans in ignition improved fuels AKZO NOBEL NV (NL) 2002-04-04 US disclosed
US-20020040108-A1 Or substituted 1,2,4-trioxacycloheptanes, to modify the rheology of a polymer such as polypropylene (PP), (visbreaking), and in the process which occurs when a flame retardant polystyrene is subjected to fire conditions AKZO NOBEL NV (NL) 2002-04-04 US disclosed
EP-0909269-A1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN WITCO CORPORATION (US) 1999-04-21 EP disclosed
EP-0909269-A1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN WITCO CORPORATION (US) 1999-04-21 EP disclosed
US-5856412-A USING 1,2,4-TRIOXACYCLOHEPTANE WITCO CORPORATION (US) 1999-01-05 US disclosed
US-5856412-A USING 1,2,4-TRIOXACYCLOHEPTANE WITCO CORPORATION (US) 1999-01-05 US disclosed
WO-1998050354-A1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN WITCO CORPORATION (US) 1998-11-12 WO disclosed
WO-1998050354-A1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN WITCO CORPORATION (US) 1998-11-12 WO disclosed
WO-1998050354-A1 PROCESS FOR CROSS-LINKING THERMOPLASTIC POLYMERS AND CROSS-LINKING SYSTEM USED THEREIN WITCO CORPORATION (US) 1998-11-12 WO disclosed