⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9442576 | 0.96 | TTR (0.36) | — | |
| Hydrogen Sulfide SCHEMBL5789620 | 0.96 | TTR (0.36) | — | |
| Tetraoxane SCHEMBL3273646 | 0.96 | TTR (0.36) | — | |
| SCHEMBL17180694 | 0.96 | — | — | |
| Cyclooctane SCHEMBL1576491 | 0.93 | TTR (0.33) | — | |
| SCHEMBL3741249 | 0.84 | ALDH1A1 (0.47) | — | |
| Cyclopentene SCHEMBL7624239 | 0.80 | — | — | |
| SCHEMBL1484296 | 0.77 | — | — | |
| SCHEMBL8994603 | 0.77 | ALDH1A1 (0.47) | — | |
| SCHEMBL20220601 | 0.77 | TTR (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8801 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119931727-A | Fuel composition and application thereof | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119868329-A | Application of endoperoxide combined with glutamine deprivation in preparation of drugs for inhibiting tumor cell metastasis of which iron death sensitivity is independent of ACSL4 | 中国人民解放军空军特色医学中心 | 2025-04-25 | — | — | CN | claimed |
| US-20250127755-A1 | PHARMACOLOGICAL DEPLETION OF HEME FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME | SCRIPPS RESEARCH INST (US) | 2025-04-24 | — | — | US | claimed |
| CN-119108620-A | Method for assembling lithium battery by polymer electrolyte | 浙江大学 | 2024-12-10 | — | — | CN | claimed |
| CN-117883436-A | Use of endoperoxides alone or in combination with respiratory chain inhibitors for the preparation of antibacterial agents | 中国科学院深圳先进技术研究院 | 2024-04-16 | — | — | CN | claimed |
| US-20240117115-A1 | POLY(CYCLIC ACETAL)S, METHODS OF MAKING SAME, AND USES THEREOF | U.S. DEPARTMENT OF ENERGY | 2024-04-11 | — | — | US | claimed |
| EP-4346803-A1 | ANTIMALARIAL ENDOPEROXIDE FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROME | The Scripps Research Institute (US) | 2024-04-10 | — | — | EP | claimed |
| CN-117712382-A | Electrode protection method, electrode and lithium battery | 蜂巢能源科技股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117460506-A | Antimalarial endoperoxides for the treatment of myelodysplastic syndromes | 斯克里普斯研究学院 | 2024-01-26 | — | — | CN | claimed |
| EP-3931288-B1 | LUBRICATING COMPOSITION FOR PREVENTING OR REDUCING PRE-IGNITION IN AN ENGINE | TOTALENERGIES ONETECH (FR) | 2023-12-20 | — | — | EP | claimed |
| US-5559145-A | TREATMENT OF MALARIA | OXACO S.A. (CH) | 1996-09-24 | — | — | US | claimed |
| EP-0338756-B1 | Use of 1,2,4-trioxanes as antiparasitics and anthelmintics | OXACO SA (CH) | 1996-03-20 | — | — | EP | claimed |
| EP-0585080-A2 | Oxygenated heterocyclic compounds, pharmaceutical compositions containing them | OXACO S.A. (CH) | 1994-03-02 | — | — | EP | claimed |
| WO-1993014756-A1 | 1,2,4-TRIOXANE COMPOUNDS HAVING ANTIMALARIAL ACTIVITY | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-08-05 | — | — | WO | claimed |
| US-5225437-A | 1,2,4-trioxane compounds having antimalarial activity | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-07-06 | — | — | US | claimed |
| EP-0286316-B1 | 1,2,4-TRIOXANE DERIVATIVES | Jefford, Charles W. (CH) | 1992-02-12 | — | — | EP | claimed |
| US-5053559-A | Synthesis or 1,2-diols | OXACO S.A. (CH) | 1991-10-01 | — | — | US | claimed |
| EP-0376737-A2 | Cleavage of 1,2,4-trioxanes | OXACO S.A. (CH) | 1990-07-04 | — | — | EP | claimed |
| EP-0338756-A2 | Use of 1,2,4-trioxanes as antiparasitics and anthelmintics | OXACO S.A. (CH) | 1989-10-25 | — | — | EP | claimed |
| EP-0286316-A1 | 1,2,4-Trioxane Derivatives | Jefford, Charles W. (CH) | 1988-10-12 | — | — | EP | claimed |