SCHEMBL3741249

SCHEMBL3741249

C1CCOCCOCCOOCOCCOCC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TTR P02766 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994603 0.94 ALDH1A1 (0.47) ALDH1A1TTR
Cyclooctane SCHEMBL1576491 0.91 TTR (0.33) TTR
SCHEMBL8862667 0.84 ALDH1A1 (0.57) ALDH1A1TTR
SCHEMBL14179993 0.84 ALDH1A1 (0.67) ALDH1A1TTR
SCHEMBL14180022 0.84 ALDH1A1 (0.67) ALDH1A1TTR
SCHEMBL14179998 0.84 ALDH1A1 (0.67) ALDH1A1TTR
SCHEMBL14180006 0.84 ALDH1A1 (0.67) ALDH1A1TTR
SCHEMBL14180020 0.84 ALDH1A1 (0.67) ALDH1A1TTR
SCHEMBL29967 0.84
Tetraoxane SCHEMBL3273646 0.81 TTR (0.36) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920070-B2 Spiro-oxazines, indolinones and preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-03-20 US disclosed
US-20170174706-A1 SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-06-22 US disclosed
US-9617280-B2 Spiro-oxazines, indolinones and preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-04-11 US disclosed
US-20160115179-A1 SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-04-28 US disclosed
WO-2014184808-A1 SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2014-11-20 WO disclosed
US-7833334-B2 Ink composition for continuous deviated jet printing Marken-Imaje (FR) 2010-11-16 US disclosed
EP-1858990-B1 INK COMPOSITION FOR CONTINUOUS DEFLECTED INK JET PRINTING IMAJE SA (FR) 2009-02-25 EP disclosed
EP-1858990-A1 INK COMPOSITION FOR CONTINUOUS DEFLECTED INK JET PRINTING IMAJE S.A. (FR) 2007-11-28 EP disclosed
US-20070248838-A1 Ink composition for continuous deviated jet printing MARKEM-IMAJE HOLDING (FR) 2007-10-25 US disclosed
WO-2006097502-A1 INK COMPOSITION FOR CONTINUOUS DEFLECTED INK JET PRINTING IMAJE S.A. (FR) 2006-09-21 WO disclosed
EP-0189803-A1 Indol-3-yl-quinazolino-1,4-benzodiazepin-5,13-diones, process for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174706-A1 SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF NR3C2, AR, REN ALDH1A1 413/4885TTR 2318/4885
US-20160115179-A1 SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF NR3C2, AR, REN ALDH1A1 413/4885TTR 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.