SCHEMBL14845107

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14842605	0.86	CACNA1G (0.44)	POLBCYP2D6CACNA1GACHEHTR3A
	SCHEMBL14854376	0.83	TP53 (0.50)	POLBCYP2D6CACNA1GACHEKDM4E
	SCHEMBL14845123	0.83	LMNA (0.43)	ACHEKDM4ESMN1; SMN2ALDH1A1MAPT
	SCHEMBL17181366	0.82	SMN1; SMN2 (0.51)	POLBCYP2D6CACNA1GACHEHTR3A
	SCHEMBL14845085	0.82	ALDH1A1 (0.50)	POLBKDM4EGAASMN1; SMN2ALDH1A1
	SCHEMBL14854386	0.81	HRH3 (0.45)	KDM4ESMN1; SMN2MAPTHSD17B10KMT2A
	SCHEMBL15991501	0.80	HRH3 (0.47)	KDM4ESMN1; SMN2MAPTHSD17B10KMT2A
	SCHEMBL14854445	0.79	POLB (0.47)	POLBCYP2D6CACNA1GACHEHTR3A
	SCHEMBL14854486	0.79	POLB (0.46)	POLBCYP2D6CACNA1GACHEHTR3A
	SCHEMBL12381245	0.76	POLB (0.68)	POLBCYP2D6CACNA1GHTR3AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.