SCHEMBL14845141

SCHEMBL14845141

CC(C)(O)C(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
TP53 P04637 1/20 0.57
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SRD5A2 P31213 4/20 0.52
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
TYR P14679 1/20 0.48
DRD1 P21728 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11298330 0.90 CA2 (0.46) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL9105008 0.83 CES1 (0.56) TSHRALDH1A1SMN1; SMN2CA1CA2
SCHEMBL21310 0.83 CES1 (0.56) TSHRALDH1A1SMN1; SMN2CA1CA2
SCHEMBL10943093 0.83 CES2 (0.50) CA2CES2CES1
SCHEMBL1665113 0.83 TSHR (0.60) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL4419639 0.83 ALDH1A1 (0.50) ALDH1A1SRD5A2CA2HPGD
SCHEMBL15251658 0.83 RXRA (0.44) SMN1; SMN2CA1CA2CA12CA9
Terephthalic Acid SCHEMBL29880581 0.82 TSHR (0.67) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL10332533 0.82 TSHR (0.75) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL10701118 0.81 CA2 (0.41) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170002100-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2017-01-05 US claimed
US-20150291707-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2015-10-15 US claimed
EP-2764027-A2 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS Lamberti SpA (IT) 2014-08-13 EP claimed
WO-2013050300-A2 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2013-04-11 WO claimed
US-10202535-B2 Method for treating subterranean formations LAMBERTI SPA (IT) 2019-02-12 US disclosed
US-20170247597-A1 METHOD FOR TREATING SUBTERRANEAN FORMATIONS LAMBERTI SPA (IT) 2017-08-31 US disclosed
US-20170002100-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2017-01-05 US disclosed
US-20170002100-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2017-01-05 US disclosed
WO-2016030165-A1 METHOD FOR TREATING SUBTERRANEAN FORMATIONS LAMBERTI SPA (IT) 2016-03-03 WO disclosed
US-20150291707-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2015-10-15 US disclosed
US-20150291707-A1 DEPOLYMERISATION OF POLYSACCHARIDES AND RELATED PRODUCTS LAMBERTI SPA (IT) 2015-10-15 US disclosed