Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956094 | 0.81 | CES2 (0.49) | CES2CES1TP53 | |
| SCHEMBL6340967 | 0.79 | — | — | |
| SCHEMBL1931609 | 0.77 | CES2 (0.47) | CES2CES1BCHERIPK1 | |
| SCHEMBL1931608 | 0.77 | CES2 (0.47) | CES2CES1BCHERIPK1 | |
| SCHEMBL7486005 | 0.74 | STAT3 (0.33) | — | |
| SCHEMBL5388423 | 0.73 | CES2 (0.67) | CES2CES1BCHERIPK1ALPL | |
| SCHEMBL1476095 | 0.72 | MEP1B (0.34) | CES2CES1 | |
| SCHEMBL2086910 | 0.72 | SLC6A12 (0.33) | — | |
| SCHEMBL1012189 | 0.72 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL1012187 | 0.72 | CES2 (0.52) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763539-A1 | ANTIBACTERIAL COMPOUNDS | Glaxo Group Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052568-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |