Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086907 | 1.00 | SLC6A12 (0.33) | SLC6A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21835003 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL19971377 | 0.75 | PIK3C3 (0.33) | — | |
| SCHEMBL1571548 | 0.74 | EGFR (0.35) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14845241 | 0.72 | CES2 (0.50) | — | |
| SCHEMBL8547431 | 0.71 | HSP90AB1 (0.43) | SLC6A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8828641 | 0.71 | CNR1 (0.43) | SLC6A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7079002 | 0.70 | CYP11B1 (0.36) | SLC6A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7079009 | 0.70 | CYP11B1 (0.36) | SLC6A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1012189 | 0.70 | CES2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163769-B2 | 1,8-naphthyridine derivatives | ABBOTT LABORATORIES (US) | 2012-04-24 | — | — | US | disclosed |