Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 13/20 | 0.51 |
| ▸ | KDR | P35968 | 11/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.49 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144561 | 0.91 | PDGFRB (0.56) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL144568 | 0.89 | KDR (0.55) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL144942 | 0.85 | KDR (0.66) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL6272302 | 0.83 | ALK (0.57) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL146207 | 0.80 | MET (0.65) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL144979 | 0.78 | KDR (0.71) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL144186 | 0.77 | FGFR1 (0.55) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL13711988 | 0.77 | KDR (0.66) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL142344 | 0.77 | KDR (0.61) | PDGFRBKDRFGFR1PRKAA1PRKAA2 | |
| SCHEMBL146649 | 0.77 | PDGFRB (0.41) | PDGFRBKDRFGFR1PRKAA1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | VERVA PHARMACEUTICALS PTY LTD (AU) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | FGF1, FABP4, FGF2 | PDGFRB 467/4885KDR 1077/4885FGFR1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.