SCHEMBL14848958

SCHEMBL14848958

CCOC(=O)COC(=O)c1cc2c(C)sc(C)c2s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
JAK2 O60674 1/20 0.43
JAK1 P23458 1/20 0.43
TYK2 P29597 1/20 0.43
JAK3 P52333 1/20 0.43
KDM4E B2RXH2 5/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
F9 P00740 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12036462 0.90 TSHR (0.51) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL14848795 0.83 L3MBTL1 (0.44) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL12036460 0.78 ESR1 (0.48) HSD17B10TSHRKDM4ENPC1MAPT
SCHEMBL15142261 0.77 CSNK2A2 (0.50) HSD17B10TSHRKDM4ETDP1L3MBTL1
SCHEMBL2241077 0.72 TSHR (0.52) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL12668159 0.71 DAO (0.53) KDM4EL3MBTL1MAPTSMN1; SMN2KMT2A
SCHEMBL18264005 0.69 HSD17B10 (0.52) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL400786 0.68 GPR35 (0.52) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL18264017 0.68 HSD17B10 (0.51) HSD17B10TSHRJAK2JAK1TYK2
SCHEMBL17434348 0.68 TSHR (0.51) HSD17B10TSHRJAK2JAK1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8941007-B2 Electron donating polymer and organic solar cell including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-01-27 US disclosed
US-8912434-B2 2014-12-16 US disclosed
US-20130087202-A1 ELECTRON DONATING POLYMER AND ORGANIC SOLAR CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-11 US disclosed