Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16611640 | 0.75 | CA1 (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20911653 | 0.75 | DRD2 (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20912151 | 0.75 | FFAR1 (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2465325 | 0.75 | LPL (0.43) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL23546470 | 0.75 | CA1 (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14852522 | 0.74 | CASP3 (0.39) | P2RX7 | |
| SCHEMBL551887 | 0.73 | SLC6A2 (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2755135 | 0.72 | CA1 (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL793416 | 0.72 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL794275 | 0.72 | ALDH1A1 (0.49) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |