Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147692 | 0.88 | SRC (0.36) | CYP2C19SMN1; SMN2SLC6A4LDHASRC | |
| SCHEMBL12983144 | 0.86 | MMP1 (0.35) | CYP2C19SMN1; SMN2SLC6A4LDHASRC | |
| SCHEMBL10141009 | 0.86 | MMP1 (0.35) | CYP2C19SMN1; SMN2SLC6A4LDHASRC | |
| SCHEMBL10228106 | 0.84 | ACACB (0.41) | CYP2C19SMN1; SMN2GAARAB9ALDHA | |
| SCHEMBL12281789 | 0.84 | ACACB (0.41) | CYP2C19SMN1; SMN2GAARAB9ALDHA | |
| SCHEMBL10140582 | 0.78 | CYP2C19 (0.35) | CYP2C19SMN1; SMN2LDHABLMANPEP | |
| SCHEMBL12841757 | 0.75 | CYP2C19 (0.35) | CYP2C19SMN1; SMN2LDHABLMPPARG | |
| SCHEMBL754142 | 0.74 | CA2 (0.46) | LDHACA2PPARG | |
| SCHEMBL12980056 | 0.74 | F2 (0.43) | GAARAB9ALDHASRCGRB2 | |
| SCHEMBL13255953 | 0.74 | F2 (0.43) | GAARAB9ALDHASRCGRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013059278-A2 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2013052369-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | WO | disclosed |