Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | GRB2 | P62993 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 5/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141009 | 1.00 | MMP1 (0.35) | MMP1SLC6A4MEN1KMT2ATAAR1 | |
| SCHEMBL10147692 | 0.88 | SRC (0.36) | MMP1SLC6A4LDHAGRB2SRC | |
| SCHEMBL14853057 | 0.86 | CYP2C19 (0.36) | MMP1SLC6A4LDHAGRB2SRC | |
| SCHEMBL12980245 | 0.84 | ACACB (0.41) | MMP1GRB2SRCZAP70 | |
| SCHEMBL8906922 | 0.84 | ACACB (0.41) | MMP1GRB2SRCZAP70 | |
| SCHEMBL10147214 | 0.79 | SLC6A4 (0.43) | SLC6A4LDHACYP2C19SMN1; SMN2ANPEP | |
| SCHEMBL13255953 | 0.74 | F2 (0.43) | MMP1LDHAGRB2SRCZAP70 | |
| SCHEMBL12980056 | 0.74 | F2 (0.43) | MMP1LDHAGRB2SRCZAP70 | |
| SCHEMBL754142 | 0.74 | CA2 (0.46) | KMT2ALDHA | |
| SCHEMBL10184219 | 0.74 | ACACB (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148006-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |