Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | GRB2 | P62993 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141009 | 0.88 | MMP1 (0.35) | SRCGRB2SLC6A4LDHACYP2C19 | |
| SCHEMBL14853057 | 0.88 | CYP2C19 (0.36) | SRCGRB2SLC6A4LDHACYP2C19 | |
| SCHEMBL12983144 | 0.88 | MMP1 (0.35) | SRCGRB2SLC6A4LDHACYP2C19 | |
| SCHEMBL13255953 | 0.84 | F2 (0.43) | SRCGRB2LDHAZAP70CA2 | |
| SCHEMBL12980056 | 0.84 | F2 (0.43) | SRCGRB2LDHAZAP70CA2 | |
| SCHEMBL10076035 | 0.79 | LAP3 (0.43) | SLC6A4LDHACYP2C19SMN1; SMN2ANPEP | |
| SCHEMBL4955861 | 0.76 | ALDH1A1 (0.43) | LDHACYP2C19SMN1; SMN2ANPEPERAP2 | |
| SCHEMBL754142 | 0.76 | CA2 (0.46) | LDHAPPARGCA2F2PLG | |
| SCHEMBL12524788 | 0.75 | ESR1 (0.51) | SLC6A4 | |
| SCHEMBL14330804 | 0.75 | F2 (0.41) | ANPEPERAP2F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | NSUN2, HCCS, HAVCR2 | SRC 3356/4885GRB2 3687/4885SLC6A4 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.