Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14857332 | 0.83 | RAB9A (0.45) | ALDH1A1POLBL3MBTL1MEN1GAA | |
| SCHEMBL14857312 | 0.78 | KMT2A (0.40) | ALDH1A1POLBL3MBTL1MEN1GAA | |
| SCHEMBL14857331 | 0.77 | TSHR (0.36) | ALDH1A1NAAAPPARG | |
| SCHEMBL14857301 | 0.77 | TSHR (0.36) | ALDH1A1NAAAPPARG | |
| SCHEMBL14857296 | 0.76 | PPARG (0.39) | ALDH1A1NAAAPPARGNPC1MAPT | |
| Olumacostat Glasaretil SCHEMBL14856848 | 0.70 | MEN1 (0.54) | ALDH1A1LTA4HMEN1KMT2APPARG | |
| SCHEMBL19821453 | 0.70 | MEN1 (0.54) | ALDH1A1LTA4HMEN1KMT2APPARG | |
| SCHEMBL19821454 | 0.70 | MEN1 (0.54) | ALDH1A1LTA4HMEN1KMT2APPARG | |
| SCHEMBL14857330 | 0.69 | THRB (0.48) | ALDH1A1GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14857326 | 0.69 | THRB (0.48) | ALDH1A1POLBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451796-B1 | TOFA ANALOGS USEFUL IN TREATING DERMATOLOGICAL DISORDERS OR CONDITIONS | DERMIRA CANADA INC (US) | 2013-04-17 | — | — | EP | claimed |