SCHEMBL14865684

SCHEMBL14865684

Cc1ccc(Oc2ccc(C(C)(c3ccc(Oc4ccc(N)cc4C(F)(F)F)cc3)C(F)(F)F)cc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
RAB9A P51151 2/20 0.40
AR P10275 7/20 0.39
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39
MAPT P10636 4/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38
FFAR1 O14842 1/20 0.37
ALDH1A1 P00352 4/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
TEAD4 Q15561 1/20 0.35
POLB P06746 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12259262 0.92 SLC6A4 (0.42) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL14865703 0.90 AR (0.45) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL15831196 0.87 AR (0.43) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL17693526 0.84 RAB9A (0.44) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL14865664 0.84 POLB (0.44) ARSLC6A4MAPTALDH1A1TEAD4
SCHEMBL12689579 0.84 POLB (0.44) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL26037439 0.84 TEAD4 (0.46) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL26037436 0.83 L3MBTL1 (0.43) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL5583700 0.82 TEAD4 (0.52) L3MBTL1RAB9AARHTR2ASLC6A4
SCHEMBL12259242 0.81 AR (0.47) L3MBTL1RAB9AARHTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369053-A1 POLYIMIDE RESIN AND METAL-CLAD LAMINATE COMPRISING THE SAME ETERNAL MATERIALS CO., LTD. (TW) 2016-12-22 US disclosed
US-20140228512-A1 POLYIMIDES, COATING COMPOSITION FORMED THEREFROM AND USE THEREOF ETERNAL CHEMICAL CO., LTD. (TW) 2014-08-14 US disclosed
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed