Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868045 | 0.89 | KDM4E (0.45) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL14868044 | 0.76 | KDM4E (0.40) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL12073545 | 0.76 | KMT2A (0.50) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL12071444 | 0.75 | ADORA2B (0.49) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL26023321 | 0.74 | HDAC8 (0.37) | KDM4EHSD17B10HPGDHTTALDH1A1 | |
| SCHEMBL12073550 | 0.74 | PDE10A (0.48) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL17874518 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL14868103 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL12071648 | 0.72 | ADORA2B (0.48) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 | |
| SCHEMBL12073548 | 0.71 | TDO2 (0.42) | SMN1; SMN2RAB9AKDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170309834-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20170309834-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-08 | — | — | US | disclosed |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-08 | — | — | US | disclosed |
| US-9379330-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9379330-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20130092922-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
| US-20130092922-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170309834-A1 | MATERIALS FOR ELECTRONIC DEVICES | SCO2, AOC2, HCN2 | SMN1; SMN2 4065/4885RAB9A 3346/4885KDM4E 1163/4885 |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | SCO2, AOC2, HCN2 | SMN1; SMN2 4065/4885RAB9A 3346/4885KDM4E 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.