SCHEMBL148710

SCHEMBL148710

O=C(Cc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
SRD5A2 P31213 2/20 0.67
FNTA P49354 1/20 0.64
FNTB P49356 1/20 0.64
DPP4 P27487 2/20 0.61
LMNA P02545 1/20 0.56
STS P08842 1/20 0.56
CES2 O00748 2/20 0.54
CA2 P00918 1/20 0.54
CAMK2A Q9UQM7 1/20 0.54
CES1 P23141 1/20 0.52
AKR1B1 P15121 1/20 0.52
PTPN1 P18031 1/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
PLAU P00749 1/20 0.51
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2063536 0.92 RAB9A (0.67) MAPTL3MBTL1NPC1RAB9ASRD5A2
Phenol SCHEMBL18694856 0.92 MAPT (0.63) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL7129800 0.91 MAPT (0.80) MAPTL3MBTL1NPC1RAB9ASRD5A2
Hydrochloric Acid SCHEMBL27845652 0.90 RAB9A (0.65) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL1642242 0.89 NPC1 (0.81) MAPTL3MBTL1NPC1RAB9ASRD5A2
Parachlorophenol SCHEMBL28159625 0.87 L3MBTL1 (0.80) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL24800 0.87 MAPT (0.73) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL27661290 0.86 NPC1 (0.70) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL5260372 0.85 SRD5A2 (0.89) MAPTL3MBTL1NPC1RAB9ASRD5A2
SCHEMBL8033816 0.85 SRD5A2 (0.89) MAPTL3MBTL1NPC1RAB9ASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113318052-A Preparation method of compound flower extract with multiple skin care effects 浙江宜格企业管理集团有限公司 2021-08-31 CN claimed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP claimed
EP-1699840-B1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-22 EP claimed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US claimed
EP-2613819-A1 Lubricious coatings for medical devices Biointeractions Ltd. (GB) 2013-07-17 EP claimed
WO-2012032283-A1 Lubricious coatings for medical devices BIOINTERACTIONS LTD (GB) 2012-03-15 WO claimed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US claimed
US-20120022177-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-01-26 US claimed
JP-4791375-B2 2011-10-12 JP claimed
US-20070238795-A1 Non-Fugitive Catalysts Containing Imine Linkages and Tertiary Amines, and Polyurethane Products made Therefrom DOW GLOBAL TECHNOLOGIES LLC 2007-10-11 US claimed
EP-1699840-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM Dow Gloval Technologies Inc. (US) 2006-09-13 EP claimed
WO-2005063840-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2005-07-14 WO claimed
US-6040484-A HYDROXYLATION OF PHENOLIC COMPOUNDS USING HYDROGEN PEROXIDE AND A CATALYST OF AT LEAST ONE RARE EARTH OR BISMUTH TRIFLATE; CATALYST SELECTIVITY RHODIA CHIMIE (FR) 2000-03-21 US claimed
US-5383050-A Optical waveguide device HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-17 US claimed
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US claimed
JP-6118462-A None JP disclosed
JP-9052860-A None JP disclosed
US-4016223-A Prostaglandin dehydrogenase inhibiting agents NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US disclosed
US-3940407-A β-Adrenergic blocking agents in the 1,2,3-thiadiazole series SYNTEX (U.S.A.) INC. (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238795-A1 Non-Fugitive Catalysts Containing Imine Linkages and Tertiary Amines, and Polyurethane Products made Therefrom UFM1, INMT, PUF60 MAPT 585/4885L3MBTL1 1747/4885NPC1 4493/4885
US-20120022177-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM UFM1, INMT, PUF60 MAPT 585/4885L3MBTL1 1747/4885NPC1 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.