Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271347 | 0.87 | LMNA (0.56) | LMNAMAPTCES2CES1NOTUM | |
| SCHEMBL13063663 | 0.87 | LMNA (0.56) | LMNAMAPTCES2CES1NOTUM | |
| SCHEMBL1549339 | 0.87 | CFTR (0.46) | LMNAADORA3MAPTCASP1NOTUM | |
| SCHEMBL2952112 | 0.85 | LMNA (0.64) | LMNAMAPTTRPV1PTPN1KDM4E | |
| SCHEMBL2267893 | 0.85 | LMNA (0.53) | LMNAADORA3MAPTTRPV1PTPN1 | |
| SCHEMBL385370 | 0.85 | LMNA (0.60) | LMNAMAPTTRPV1CES2CES1 | |
| Ammonia Solution, Strong SCHEMBL27316369 | 0.84 | LMNA (0.59) | LMNAMAPTTRPV1CES2CES1 | |
| SCHEMBL5203797 | 0.82 | ALDH1A1 (0.51) | LMNAMAPTTP53PTPN1KDM4E | |
| SCHEMBL5203117 | 0.82 | ABCG2 (0.58) | LMNAMAPTABCG2TDP1KDM4E | |
| SCHEMBL29893354 | 0.81 | LMNA (0.47) | LMNAADORA3SIRT5MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013054302-A1 | METHOD FOR PREPARING TRIARYL(HETEROARYL)BISMUTHS, AND USES THEREOF FOR THE SYNTHESIS OF AROMATIC OR HETEROAROMATIC DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-04-18 | — | — | WO | disclosed |