SCHEMBL13063663

SCHEMBL13063663

COC(=O)c1ccc(-c2ccc(-c3ccc(-c4ccc(C(F)(F)F)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
CA12 O43570 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
PTPN1 P18031 2/20 0.53
TDP1 Q9NUW8 1/20 0.52
CA7 P43166 1/20 0.52
MAPT P10636 1/20 0.52
NOTUM Q6P988 2/20 0.51
KIF11 P52732 4/20 0.50
CFTR P13569 1/20 0.50
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271347 1.00 LMNA (0.56) LMNACES2CES1CA1CA2
SCHEMBL385370 0.94 LMNA (0.60) LMNACES2CES1CA1CA2
Ammonia Solution, Strong SCHEMBL27316369 0.92 LMNA (0.59) LMNACES2CES1CA1CA2
SCHEMBL2389365 0.88 RXRA (0.65) LMNACA1CA2CA12CA9
SCHEMBL31575935 0.87 SRD5A2 (0.65) LMNACES2CES1CA1CA2
Methylene Chloride SCHEMBL28147089 0.87 LMNA (0.55) LMNACES2CES1CA1CA2
SCHEMBL14872141 0.87 LMNA (0.52) LMNACES2CES1CA1CA2
SCHEMBL1782842 0.86 LMNA (0.69) LMNACES2CES1CA1CA2
SCHEMBL7847608 0.86 PTPN1 (0.60) LMNACES2CES1CA1CA2
Bromoethane SCHEMBL27454009 0.86 NOTUM (0.57) LMNACES2CES1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905260-B2 Method for manufacturing optical information recording medium FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed
US-9711176-B2 Multilayer optical information recording disk and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-07-18 US disclosed
US-9514779-B2 Method for manufacturing multilayer structure sheet, and optical information recording medium FUJIFILM CORPORATION (JP) 2016-12-06 US disclosed
US-20150364153-A1 METHOD FOR MANUFACTURING OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-20150318013-A1 MULTILAYER OPTICAL INFORMATION RECORDING DISK AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-8980396-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-03-17 US disclosed
US-8953427-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-02-10 US disclosed
US-20140193601-A1 METHOD FOR MANUFACTURING MULTILAYER STRUCTURE SHEET, AND OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-07-10 US disclosed
US-20140153375-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR MANUFACTURING SAME AND RECORDING METHOD FOR OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-06-05 US disclosed
US-8670296-B2 Optical information recording medium and optical information recording method FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-20140023816-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
US-20130229901-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-09-05 US disclosed
US-8526291-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-20130128710-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
US-20130100791-A1 OPTICAL INFORMATION RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-25 US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND SIGMAR1, SFN, CRY2 LMNA 1647/4885CES2 1800/4885CES1 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.