Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48345 | 0.75 | ALDH1A1 (0.62) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL20034632 | 0.75 | ALDH1A1 (0.34) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL25098658 | 0.74 | CA2 (0.40) | ALDH1A1CA1CA12CA2CA14 | |
| SCHEMBL3217919 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL3151454 | 0.73 | ALDH1A1 (0.60) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL8981500 | 0.73 | ALDH1A1 (0.60) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL16438219 | 0.73 | ALDH1A1 (0.60) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL8018138 | 0.73 | ALDH1A1 (0.60) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL11033708 | 0.73 | ALDH1A1 (1.00) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL27183099 | 0.71 | ALDH1A1 (0.58) | ALDH1A1PRMT3CARM1PRMT6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301933-A1 | Thiopyrimidine derivative, useful as an intermediate for chemokine receptor modulators | AstraZeneca AB (SE) | 2011-03-30 | — | — | EP | disclosed |