SCHEMBL148738

SCHEMBL148738

C/C(=C\c1ccccc1)NC(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.57
RECQL P46063 1/20 0.49
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
MCL1 Q07820 1/20 0.44
MTNR1A P48039 2/20 0.44
MTNR1B P49286 2/20 0.44
HTT P42858 2/20 0.43
FBP1 P09467 1/20 0.43
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
DHODH Q02127 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
AKR1C1 Q04828 1/20 0.41
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148740 1.00 AKR1C3 (0.57) AKR1C3RECQLALDH1A1TSHRMCL1
SCHEMBL259946 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL19435785 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL19435787 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL8039408 0.82 AKR1C3 (0.40) AKR1C3RECQLALDH1A1TSHRMCL1
SCHEMBL14123656 0.78 AKR1C3 (0.53) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL12718585 0.78 AKR1C3 (0.53) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL9318251 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL10363546 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL9775586 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10279069-B2 Shape memory polymer articles with a microstructured surface 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-05-07 US disclosed
EP-2046556-B1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2015-11-18 EP disclosed
US-8236226-B2 Methods for changing the shape of a surface of a shape memory polymer article 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-07 US disclosed
US-20120058305-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M INNOVATIVE PROPERTIES COMPANY 2012-03-08 US disclosed
US-20110198781-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY 2011-08-18 US disclosed
US-7951319-B2 Methods for changing the shape of a surface of a shape memory polymer article 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-31 US disclosed
EP-2046408-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M Innovative Properties Company (US) 2009-04-15 EP disclosed
EP-2046556-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M Innovative Properties Company (US) 2009-04-15 EP disclosed
WO-2008014109-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-31 WO disclosed
US-20080027199-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed
WO-2008014167-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-31 WO disclosed
US-20080023890-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed