SCHEMBL148740

SCHEMBL148740

CC(=Cc1ccccc1)NC(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.57
RECQL P46063 1/20 0.49
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
MCL1 Q07820 1/20 0.44
MTNR1A P48039 2/20 0.44
MTNR1B P49286 2/20 0.44
HTT P42858 2/20 0.43
FBP1 P09467 1/20 0.43
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
DHODH Q02127 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
AKR1C1 Q04828 1/20 0.41
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148738 1.00 AKR1C3 (0.57) AKR1C3RECQLALDH1A1TSHRMCL1
SCHEMBL259946 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL19435785 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL19435787 0.84 AKR1C3 (0.61) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL8039408 0.82 AKR1C3 (0.40) AKR1C3RECQLALDH1A1TSHRMCL1
SCHEMBL14123656 0.78 AKR1C3 (0.53) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL12718585 0.78 AKR1C3 (0.53) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL9318251 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL10363546 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL9775586 0.77 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111108154-B Silicone pressure-sensitive adhesive 3M创新有限公司 2022-01-28 CN disclosed
EP-3688098-B1 PHOTO-RADICAL CURE OF SILICONES 3M INNOVATIVE PROPERTIES CO (US) 2020-12-23 EP disclosed
EP-3688099-B1 SILICONE-BASED PRESSURE-SENSITIVE ADHESIVE 3M INNOVATIVE PROPERTIES CO (US) 2020-12-09 EP disclosed
US-10836934-B2 Photo-radical cure of silicones 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-17 US disclosed
US-10822532-B2 Silicone-based pressure-sensitive adhesive 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-03 US disclosed
US-20200270494-A1 SILICONE-BASED PRESSURE-SENSITIVE ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY 2020-08-27 US disclosed
US-20200248034-A1 PHOTO-RADICAL CURE OF SILICONES 3M INNOVATIVE PROPERTIES COMPANY 2020-08-06 US disclosed
EP-3688098-A1 PHOTO-RADICAL CURE OF SILICONES 3M Innovative Properties Company (US) 2020-08-05 EP disclosed
EP-3688099-A1 SILICONE-BASED PRESSURE-SENSITIVE ADHESIVE 3M Innovative Properties Company (US) 2020-08-05 EP disclosed
CN-111148795-A Photoradical cure of silicones 3M创新有限公司 2020-05-12 CN disclosed
US-5475124-A Fluorosilane compounds useful as terminating agents in anionic siloxane polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-12 US disclosed
US-5314748-A Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING & MANUFACTURING COMPANY (US) 1994-05-24 US disclosed
EP-0583259-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING. MINNESOTA MINING & MFG (US) 1994-02-23 EP disclosed
EP-0576544-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
US-5264278-A Low temperature adhesion, shock resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-23 US disclosed
US-5237082-A Amine subsituted fluorosilanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-17 US disclosed
WO-1992016590-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016593-A2 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
US-5091483-A Controllability and stability of rapidly-cured telechelic polymers containing ethylenic, amido, ester and/or urea groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-25 US disclosed
EP-0421643-A2 Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-04-10 EP disclosed