Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363546 | 1.00 | AKR1C3 (0.52) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL14123656 | 0.84 | AKR1C3 (0.53) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL259946 | 0.80 | AKR1C3 (0.61) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL19435785 | 0.80 | AKR1C3 (0.61) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL19435787 | 0.80 | AKR1C3 (0.61) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL9775580 | 0.78 | AKR1C1 (0.44) | AKR1C3ALDH1A1MTNR1AMTNR1BHTT | |
| SCHEMBL9775578 | 0.78 | AKR1C1 (0.44) | AKR1C3ALDH1A1MTNR1AMTNR1BHTT | |
| SCHEMBL7664129 | 0.77 | GLA (0.38) | AKR1C3RECQLALDH1A1TSHRHTT | |
| SCHEMBL148740 | 0.77 | AKR1C3 (0.57) | AKR1C3RECQLALDH1A1TSHRMTNR1A | |
| SCHEMBL148738 | 0.77 | AKR1C3 (0.57) | AKR1C3RECQLALDH1A1TSHRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |