SCHEMBL8039408

SCHEMBL8039408

C/C(=C\c1ccccc1)NC(N)=O.C1CC[SiH2]OC1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.40
RECQL P46063 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
MCL1 Q07820 1/20 0.33
KDM1A O60341 1/20 0.33
HPGD P15428 2/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148738 0.82 AKR1C3 (0.57) AKR1C3RECQLALDH1A1TSHRMTNR1A
SCHEMBL148740 0.82 AKR1C3 (0.57) AKR1C3RECQLALDH1A1TSHRMTNR1A
Benzamide SCHEMBL7593263 0.73 PARP1 (0.53) RECQLALDH1A1TSHRHPGDLMNA
Cinnamic Acid SCHEMBL6918836 0.72 HCAR2 (0.58) RECQLPKMKMT2AMEN1ALDH1A1
Cinnamic Acid SCHEMBL6918830 0.72 HCAR2 (0.58) RECQLPKMKMT2AMEN1ALDH1A1
Styrene SCHEMBL11156150 0.71 ALDH1A1 (0.41) AKR1C3KMT2AMEN1ALDH1A1TSHR
Carbamic Acid SCHEMBL27869277 0.70 ACHE (0.33)
Acetic Acid SCHEMBL27129104 0.70 FFAR3 (0.33)
Benzoic Acid SCHEMBL11531927 0.70 TSHR (0.50) AKR1C3PKMKMT2AMEN1ALDH1A1
SCHEMBL19435785 0.69 AKR1C3 (0.61) AKR1C3RECQLKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421643-B1 Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING & MFG (US) 2000-12-27 EP disclosed
EP-0576544-B1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1997-06-04 EP disclosed
EP-0576579-B1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES MINNESOTA MINING & MFG (US) 1995-11-15 EP disclosed
EP-0583259-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING. MINNESOTA MINING & MFG (US) 1994-02-23 EP disclosed
EP-0576579-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
EP-0576544-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
US-5264278-A Low temperature adhesion, shock resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-23 US disclosed
WO-1992016590-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016593-A2 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016591-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COATED TAPES ADHERABLE TO PAINT COATED SUBSTRATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
EP-0421643-A2 Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-04-10 EP disclosed