Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435785 | 1.00 | AKR1C3 (0.61) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19435787 | 1.00 | AKR1C3 (0.61) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL148738 | 0.84 | AKR1C3 (0.57) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL148740 | 0.84 | AKR1C3 (0.57) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12718585 | 0.81 | AKR1C3 (0.53) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14123656 | 0.81 | AKR1C3 (0.53) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL786716 | 0.80 | AKR1C3 (0.57) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL388143 | 0.80 | AKR1C3 (0.57) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12561790 | 0.80 | RECQL (0.53) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL388142 | 0.80 | AKR1C3 (0.57) | AKR1C3RECQLMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067642-B2 | Chiral phosphorous compounds | Celtice Catalysts Limited, Nova UCD (IE) | 2011-11-29 | — | — | US | disclosed |
| US-20100168456-A1 | CHIRAL PHOSPHOROUS COMPOUNDS | CELTIC CATALYSTS LIMITED (IE) | 2010-07-01 | — | — | US | disclosed |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | disclosed |
| US-20090326253-A1 | NOVEL PHOSPHINE LIGANDS | IDING HANS | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | AKR1C3 2816/4885RECQL 1889/4885MTNR1A 4134/4885 |
| US-20100168456-A1 | CHIRAL PHOSPHOROUS COMPOUNDS | RPP30, PLCB3, INPP5D | AKR1C3 401/4885RECQL 2536/4885MTNR1A 3168/4885 |
| US-20090326253-A1 | NOVEL PHOSPHINE LIGANDS | PRMT8, GRB7, STK38L | AKR1C3 1958/4885RECQL 2208/4885MTNR1A 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.