SCHEMBL14874353

SCHEMBL14874353

CCCC(c1ccccc1OC)C(C)(C)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.42
▸ MAPT P10636 2/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ PLIN1 O60240 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ PLIN5 Q00G26 1/20 0.42
▸ ABHD5 Q8WTS1 1/20 0.42
▸ TSHR P16473 2/20 0.41
▸ HTT P42858 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ TAS1R3 Q7RTX0 1/20 0.39
▸ TAS1R1 Q7RTX1 1/20 0.39
▸ PIN1 Q13526 1/20 0.39
▸ PRSS1 P07477 1/20 0.39
▸ CTSG P08311 1/20 0.39
▸ CTRB1 P17538 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874454 0.88 POLB (0.39) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874404 0.88 POLB (0.42) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874564 0.88 GAA (0.40) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874479 0.86 PIN1 (0.38) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874461 0.85 ITGA4 (0.45) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874508 0.85 TSHR (0.39) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874445 0.84 KMT2A (0.44) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874432 0.84 TSHR (0.39) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874488 0.83 TSHR (0.40) POLBMAPTMEN1KMT2APLIN1
SCHEMBL14874611 0.81 TSHR (0.39) POLBMAPTMEN1KMT2APLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
CN-104254551-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA 2014-12-31 — — CN disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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