SCHEMBL14874454

SCHEMBL14874454

CCCC(c1ccccc1OC)C(C)(CC)C(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ PLIN1 O60240 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ PLIN5 Q00G26 1/20 0.39
▸ ABHD5 Q8WTS1 1/20 0.39
▸ TSHR P16473 3/20 0.39
▸ HTT P42858 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ TAS1R3 Q7RTX0 1/20 0.37
▸ TAS1R1 Q7RTX1 1/20 0.37
▸ PIN1 Q13526 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ CNR2 P34972 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874508 0.89 TSHR (0.39) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874353 0.88 POLB (0.42) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874649 0.85 KMT2A (0.43) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874582 0.85 ITGA4 (0.43) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874479 0.85 PIN1 (0.38) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874404 0.85 POLB (0.42) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874564 0.85 GAA (0.40) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874488 0.82 TSHR (0.40) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874432 0.81 TSHR (0.39) POLBMEN1KMT2AMAPTPLIN1
SCHEMBL14874612 0.81 MEN1 (0.40) POLBMEN1KMT2AMAPTPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
CN-104254551-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2016-08-17 — — CN disclosed
CN-104254551-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA 2014-12-31 — — CN disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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