SCHEMBL14874433

SCHEMBL14874433

CCOC(=O)C(Cc1ccccc1OC)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ GAA P10253 1/20 0.46
▸ MEN1 O00255 3/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ LMNA P02545 1/20 0.44
▸ HPGD P15428 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655892 0.77 LMNA (0.48) POLBGAAMEN1KMT2ALMNA
SCHEMBL2673221 0.77 ALDH1A1 (0.49) POLBTSHRGAAMEN1KMT2A
SCHEMBL18342037 0.76 CYP1A2 (0.48) POLBTSHRGAAMEN1KMT2A
SCHEMBL28582434 0.76 CYP1A2 (0.48) POLBTSHRGAAMEN1KMT2A
SCHEMBL747405 0.76 TSHR (0.51) POLBTSHRGAAMEN1KMT2A
SCHEMBL28584327 0.76 CYP1A2 (0.48) POLBTSHRGAAMEN1KMT2A
SCHEMBL7975883 0.75 POLB (0.47) POLBGAAMEN1KMT2AL3MBTL1
SCHEMBL14874367 0.75 TSHR (0.51) POLBTSHRMEN1KMT2ALMNA
SCHEMBL14874551 0.74 ALDH1A1 (0.57) TSHRMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL20543840 0.74 ALDH1A1 (0.47) POLBTSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
CN-104254551-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2016-08-17 — — CN disclosed
CN-104254551-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA 2014-12-31 — — CN disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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