SCHEMBL2673221

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2426744	0.92	ALDH1A1 (0.46)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL30036768	0.92	ALDH1A1 (0.46)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL20212336	0.87	MTNR1A (0.51)	ALDH1A1TSHRMEN1KMT2AMAPT
	SCHEMBL20223077	0.86	ALDH1A1 (0.41)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL20212191	0.86	CYP4F2 (0.45)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL491027	0.86	LMNA (0.52)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL19502670	0.86	MMP8 (0.54)	ALDH1A1TDP1TSHRMEN1KMT2A
	SCHEMBL18342037	0.86	CYP1A2 (0.48)	ALDH1A1TSHRMEN1KMT2AMAPT
	SCHEMBL28582434	0.86	CYP1A2 (0.48)	ALDH1A1TSHRMEN1KMT2AMAPT
	SCHEMBL747405	0.86	TSHR (0.51)	ALDH1A1TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.