Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442518 | 0.88 | ALDH1A1 (0.70) | MAPK1RXFP1ALDH1A1TDP1POLB | |
| SCHEMBL14874458 | 0.87 | ALDH1A1 (0.54) | MAPK1HTTRXFP1ALDH1A1TDP1 | |
| SCHEMBL6016291 | 0.82 | RXFP1 (0.62) | RXFP1POLBMAPT | |
| SCHEMBL22451091 | 0.81 | PDE4B (0.66) | MAPK1HTTALDH1A1TDP1POLB | |
| SCHEMBL2953742 | 0.81 | ALDH1A1 (0.58) | MAPK1HTTALDH1A1TDP1POLB | |
| SCHEMBL6338112 | 0.80 | SYK (0.80) | MAPK1HTTALDH1A1TDP1POLB | |
| SCHEMBL10433933 | 0.80 | ALDH1A1 (0.86) | MAPK1ALDH1A1POLBMAPTLMNA | |
| SCHEMBL5711053 | 0.79 | ALDH1A1 (0.58) | MAPK1RXFP1ALDH1A1TDP1POLB | |
| SCHEMBL5679891 | 0.79 | ALDH1A1 (0.52) | MAPK1HTTALDH1A1TDP1POLB | |
| SCHEMBL6879275 | 0.78 | NPSR1 (0.63) | MAPK1HTTALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583965-B1 | HETEROCYCLIC RING COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-8937055-B2 | Heterocyclic ring compound having muscle cell or adipocyte differentiation regulating action | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20130296276-A2 | HETEROCYCLIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130116214-A1 | HETEROCYCLIC RING COMPOUND | UJIKAWA OSAMU (JP) | 2013-05-09 | — | — | US | disclosed |
| EP-2583965-A1 | HETEROCYCLIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2013-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116214-A1 | HETEROCYCLIC RING COMPOUND | FABP4, CPT1B, GPR119 | MAPK1 1130/4885HTT 1741/4885RXFP1 1548/4885 |
| US-20130296276-A2 | HETEROCYCLIC RING COMPOUND | FABP4, CPT1B, GPR119 | MAPK1 1130/4885HTT 1741/4885RXFP1 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.