Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573122 | 0.94 | ALDH1A1 (0.49) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL14874901 | 0.86 | MAPT (0.35) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL14874900 | 0.83 | RAB9A (0.49) | ALDH1A1MAPTALOX15NPC1RAB9A | |
| SCHEMBL14573121 | 0.77 | LSS (0.39) | MMP12SMN1; SMN2USP9XKCNH2HRH3 | |
| SCHEMBL961792 | 0.75 | KCNN4 (0.44) | ALDH1A1MMP12HPGDSMN1; SMN2USP9X | |
| Styrene SCHEMBL27729578 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRMMP12HPGDSMN1; SMN2 | |
| SCHEMBL84185 | 0.75 | KCNN4 (0.47) | ALDH1A1MMP12NPC1RAB9AHPGD | |
| SCHEMBL21351777 | 0.75 | KCNN4 (0.47) | ALDH1A1MMP12NPC1RAB9AHPGD | |
| SCHEMBL5611161 | 0.74 | NOTUM (0.44) | ALDH1A1MAPTRECQLNPC1RAB9A | |
| SCHEMBL28865459 | 0.74 | KCNH2 (0.42) | SMN1; SMN2USP9XKCNH2HRH3LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802593-B1 | POLYMER-FILLER COUPLING ADDITIVES | BRIDGESTONE CORP (JP) | 2013-04-24 | — | — | EP | claimed |
| CN-105367509-A | Polymer-filler coupling additives | BRIDGESTONE CORP | 2016-03-02 | — | — | CN | disclosed |
| CN-101084202-B | Polymer-Filler Coupling Additives | BRIDGESTONE CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| US-20140316132-A1 | MODULATORS OF TOLL-LIKE RECEPTORS | GILEAD SCIENCES, INC. | 2014-10-23 | — | — | US | disclosed |
| EP-1802593-B1 | POLYMER-FILLER COUPLING ADDITIVES | BRIDGESTONE CORP (JP) | 2013-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140316132-A1 | MODULATORS OF TOLL-LIKE RECEPTORS | TLR3, TLR2, TLR6 | G6PD 2071/4885ALDH1A1 3435/4885MAPT 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.