Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874985 | 0.86 | LMNA (0.50) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL14875025 | 0.86 | G6PD (0.49) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL14875038 | 0.86 | RAB9A (0.46) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL14874969 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPC1RAB9ANFKB1 | |
| SCHEMBL9329758 | 0.80 | MAPT (0.45) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL11404254 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14874901 | 0.74 | MAPT (0.35) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL14777410 | 0.72 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL14777411 | 0.72 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL5610907 | 0.69 | PDPK1 (0.41) | NPC1RAB9AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367509-A | Polymer-filler coupling additives | BRIDGESTONE CORP | 2016-03-02 | — | — | CN | claimed |
| EP-1802593-B1 | POLYMER-FILLER COUPLING ADDITIVES | BRIDGESTONE CORP (JP) | 2013-04-24 | — | — | EP | claimed |
| CN-105367509-A | Polymer-filler coupling additives | BRIDGESTONE CORP | 2016-03-02 | — | — | CN | disclosed |
| CN-101084202-B | Polymer-Filler Coupling Additives | BRIDGESTONE CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| EP-1802593-B1 | POLYMER-FILLER COUPLING ADDITIVES | BRIDGESTONE CORP (JP) | 2013-04-24 | — | — | EP | disclosed |