Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 1.00 |
| ▸ | CCKAR | P32238 | 13/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | TSPO | P30536 | 1/20 | 1.00 |
| ▸ | GLP1R | P43220 | 1/20 | 1.00 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 2/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.64 |
| ▸ | PDE5A | O76074 | 1/20 | 0.64 |
| ▸ | PDE1A | P54750 | 1/20 | 0.64 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.64 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Devazepide SCHEMBL4884074 | 1.00 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL6255769 | 1.00 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL29406251 | 1.00 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL31616311 | 1.00 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL8613468 | 1.00 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL8437864 | 0.94 | CCKBR (0.88) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9842437 | 0.94 | CCKBR (0.88) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9422963 | 0.91 | CCKBR (0.83) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL7143510 | 0.90 | CCKBR (0.82) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL7143513 | 0.90 | CCKBR (0.82) | CCKBRCCKARADRB2TSPOGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186634-A1 | METHODS OF TREATING SMALL CELL LUNG CANCER | Evergreen Discovery, LLC (US) | 2025-06-12 | — | — | US | claimed |
| WO-2025122363-A2 | METHODS OF TREATING SMALL CELL LUNG CANCER | Evergreen Discovery, LLC (US) | 2025-06-12 | — | — | WO | claimed |
| US-20250082649-A1 | ALTERATION OF NUTRIENT PREFERENCES VIA MODULATION OF NUTRIENT RECEPTORS IN THE GUT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2025-03-13 | — | — | US | claimed |
| WO-2024256731-A2 | A CHOLECYSTOKININ (CCK) ANTAGONIST FOR USE IN THE PREVENTION AND/OR TREATMENT OF A VESTIBULAR DISEASE OR DISORDER | UNIVERSITAT AUTONOMA DE BARCELONA (ES) | 2024-12-19 | — | — | WO | claimed |
| EP-4477218-A1 | A CHOLECYSTOKININ (CCK) ANTAGONIST FOR USE IN THE PREVENTION AND/OR TREATMENT OF A VESTIBULAR DISEASE OR DISORDER | Universitat Autònoma de Barcelona (ES) | 2024-12-18 | — | — | EP | claimed |
| WO-2023164661-A1 | ALTERATION OF NUTRIENT PREFERENCES VIA MODULATION OF NUTRIENT RECEPTORS IN THE GUT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-08-31 | — | — | WO | claimed |
| WO-2019018438-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF GUT SENSORY CELLS | DUKE UNIVERSITY (US) | 2019-01-24 | — | — | WO | claimed |
| CN-105687203-B | Application of cholecystokinin receptor inhibitor Devazepide in preparation of anti-fibrosis pharmaceutical preparation | 无锡市人民医院 | 2018-07-10 | — | — | CN | claimed |
| CN-105687203-A | Application of cholecystokinin receptor inhibitor Devazepide in preparation of anti-fibrosis pharmaceutical preparation | 无锡市人民医院 | 2016-06-22 | — | — | CN | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-1023072-B1 | ANALGESIC COMPOSITIONS COMPRISING A CHOLECYSTOKININ AND AN OPIOID | PANOS THERAPEUTICS LTD (GB) | 2002-12-11 | — | — | EP | claimed |
| EP-0730453-A4 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO INC (US) | 1998-03-04 | — | — | EP | claimed |
| EP-0730453-A1 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | claimed |
| US-5428031-A | Benzodiazepine analogs; cardiovascular disorders | MERCK & CO., INC. (US) | 1995-06-27 | — | — | US | claimed |
| WO-1995014470-A1 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | claimed |
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | claimed |
| WO-1993003717-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-5153191-A | Administering lorglumide or loxiglumide or salts thereof | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186634-A1 | METHODS OF TREATING SMALL CELL LUNG CANCER | SSTR2, CCKBR, GRPR | CCKBR 2/4885CCKAR 4/4885ADRB2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.