Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.88 |
| ▸ | CCKAR | P32238 | 13/20 | 0.88 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.88 |
| ▸ | TSPO | P30536 | 1/20 | 0.88 |
| ▸ | GLP1R | P43220 | 1/20 | 0.88 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.88 |
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | PDE1A | P54750 | 1/20 | 0.57 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.57 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842437 | 1.00 | CCKBR (0.88) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL4884074 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL148766 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL29406251 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL31616311 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL6255769 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| Devazepide SCHEMBL8613468 | 0.94 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9842213 | 0.86 | CCKBR (0.77) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9525757 | 0.86 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9525603 | 0.86 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730453-A4 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO INC (US) | 1998-03-04 | — | — | EP | claimed |
| EP-0730453-A1 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1995014470-A1 | METHODS OF TREATING CARDIAC ARRHYTHMIA | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | claimed |
| US-5929071-A | Method for the treatment of preterm labor | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |