Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067276 | 0.79 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL2827545 | 0.76 | GAA (0.39) | AXLGAARECQL | |
| SCHEMBL21990910 | 0.71 | — | — | |
| SCHEMBL8911551 | 0.62 | — | — | |
| SCHEMBL89524 | 0.62 | — | — | |
| SCHEMBL16554341 | 0.62 | — | — | |
| SCHEMBL20095237 | 0.62 | — | — | |
| SCHEMBL20349165 | 0.61 | GPR119 (0.32) | — | |
| SCHEMBL3186703 | 0.60 | SMN1; SMN2 (0.38) | GAARECQL | |
| SCHEMBL16981313 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299463-B2 | Process for the manufacture of pyrazoles or pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2022-04-12 | — | — | US | disclosed |
| EP-3650443-A1 | CONTINUOUS FLOW SYNTHESIS OF FLUORINATED OR NON-FLUORINATED PYRAZOLES | Fujian Yongjing Technology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| EP-3650443-A1 | CONTINUOUS FLOW SYNTHESIS OF FLUORINATED OR NON-FLUORINATED PYRAZOLES | Fujian Yongjing Technology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-05-07 | — | — | US | disclosed |
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-05-07 | — | — | US | disclosed |
| CN-110452173-A | A kind of new method for manufacturing pyrazoles or pyrimidone | FUJIAN YONGJING TECH CO LTD | 2019-11-15 | — | — | CN | disclosed |
| EP-3148972-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | Cardioxyl Pharmaceuticals Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015183839-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| EP-2475652-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | Cylene Pharmaceuticals, Inc. (US) | 2012-07-18 | — | — | EP | disclosed |
| EP-2050745-B1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | OTSUKA AGRITECHNO CO LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7994094-B2 | N-pyridylpiperidine compound, method for producing the same, and pest control agent | OTSUKA AGRITECHNO CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994094-B2 | N-pyridylpiperidine compound, method for producing the same, and pest control agent | OTSUKA AGRITECHNO CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20110071115-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| WO-2011031979-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | CYLENE PHARMACEUTICALS INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20100137582-A1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100137582-A1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2050745-A1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | Otsuka Chemical Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | DHFR, CYP4X1, CYP2F1 | AXL 3323/4885TDP2 3045/4885GAA 3879/4885 |
| US-20110071115-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | PIM2, PIM1, PIM3 | AXL 1446/4885TDP2 3027/4885GAA 1865/4885 |
| US-20100137582-A1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | HRH4, NOX4, PRDX4 | AXL 2372/4885TDP2 3161/4885GAA 4316/4885 |
| US-11299463-B2 | Process for the manufacture of pyrazoles or pyrimidones | DHFR, CYP4X1, CYP2F1 | AXL 3230/4885TDP2 3077/4885GAA 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.