SCHEMBL14878232

SCHEMBL14878232

CNC(=O)COP(=O)(O)O

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.64
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
LPAR3 Q9UBY5 3/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR2 Q9HBW0 2/20 0.35
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
MCL1 Q07820 1/20 0.34
LMNA P02545 1/20 0.34
PGD P52209 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760365 0.79 ALDH1A1 (0.42) TPI1MMP2MMP3MMP8LPAR3
Phosphoglycolohydroxamate SCHEMBL4309631 0.78 TPI1 (1.00) TPI1PGD
SCHEMBL5200023 0.76 ALDH1A1 (0.40) TPI1MMP2MMP3MMP8ALDH1A1
SCHEMBL10067496 0.73 TPI1 (0.54) TPI1LPAR3LPAR1LPAR2PGK1
SCHEMBL7760362 0.73 ALDH1A1 (0.50) TPI1ALDH1A1MAPTLMNABCHE
SCHEMBL5804165 0.73 ALDH1A1 (0.50) TPI1ALDH1A1MAPTLMNABCHE
SCHEMBL160921 0.72
SCHEMBL25833481 0.71 TPI1 (0.38) TPI1MMP2MMP3MMP8ALDH1A1
SCHEMBL10932356 0.71 ALDH1A1 (0.48) TPI1ALDH1A1MAPTMCL1LMNA
SCHEMBL13411713 0.71 LMNA (0.42) ALDH1A1MAPTMCL1LMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367910-A1 PACKING MATERIAL FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY SHISEIDO COMPANY, LTD. (JP) 2016-12-22 US disclosed
US-8426627-B2 Phosphorylcholine group-containing compound and surface modifying agent composed of such compound SHISEIDO COMPANY, LTD. (JP) 2013-04-23 US disclosed