Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969894 | 0.86 | LMNA (0.41) | TSHRLMNAF2PLA2G7AKT1 | |
| SCHEMBL19244943 | 0.79 | KMT2A (0.35) | TDP1ALDH1A1HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL23754765 | 0.76 | TSHR (0.50) | TSHRLMNAF2PLA2G7AKT1 | |
| SCHEMBL2502087 | 0.76 | TSHR (0.50) | TSHRLMNAF2PLA2G7AKT1 | |
| SCHEMBL18873040 | 0.73 | KMT2A (0.34) | TDP1ALDH1A1HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL14649904 | 0.73 | KMT2A (0.34) | TDP1ALDH1A1HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL13621556 | 0.72 | CES2 (0.43) | LMNAAKT1ALDH1A1RAB9ACYP3A4 | |
| SCHEMBL13478795 | 0.72 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL20646376 | 0.72 | KMT2A (0.44) | TSHRLMNATDP1ALDH1A1HSD17B10 | |
| SCHEMBL24203432 | 0.71 | AKT1 (0.44) | TSHRLMNAF2PLA2G7AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426102-B2 | Lithographic printing plate precursor and plate making method | FUJIFILM CORPORATION (JP) | 2013-04-23 | — | — | US | disclosed |