SCHEMBL25969894

SCHEMBL25969894

C=C/C=C\C(=C/C=C)OC(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
F2 P00734 1/20 0.41
TSHR P16473 5/20 0.39
AKT1 P31749 1/20 0.39
TDP1 Q9NUW8 5/20 0.36
TP53 P04637 1/20 0.36
PLA2G7 Q13093 2/20 0.36
PARP10 Q53GL7 1/20 0.36
KMT2A Q03164 4/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 3/20 0.35
POLB P06746 2/20 0.35
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HSD17B10 Q99714 2/20 0.34
CYP3A4 P08684 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14878255 0.86 TSHR (0.42) LMNAF2TSHRAKT1TDP1
SCHEMBL18629181 0.78 THRB (0.36) TDP1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL9909074 0.77 LMNA (0.41) LMNAF2TSHRAKT1TDP1
SCHEMBL20746724 0.75 TSHR (0.41) LMNAF2TSHRAKT1TDP1
SCHEMBL19034285 0.75
SCHEMBL19558477 0.73 THRB (0.34) TSHRTDP1KMT2AHSD17B10L3MBTL1
SCHEMBL24203432 0.72 AKT1 (0.44) LMNAF2TSHRAKT1TDP1
SCHEMBL7050451 0.72 LMNA (0.67) LMNAF2TSHRTDP1TP53
SCHEMBL18594635 0.72
SCHEMBL1534569 0.72 LMNA (0.67) LMNAF2TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230260787-A1 COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-17 US disclosed