Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905513 | 0.92 | MMP1 (0.40) | OPRM1OPRD1OPRK1HRH3MMP1 | |
| SCHEMBL328486 | 0.91 | MMP1 (0.53) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL14878482 | 0.87 | MMP1 (0.43) | HRH3MMP1MMP3MMP7MMP9 | |
| SCHEMBL12905512 | 0.80 | MMP1 (0.42) | HRH3MMP1MMP3MMP7MMP9 | |
| SCHEMBL778953 | 0.78 | MMP1 (0.55) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL328467 | 0.77 | MMP1 (0.50) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL14878483 | 0.75 | F2R (0.41) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL14878466 | 0.74 | MMP1 (0.44) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL14878456 | 0.73 | MMP1 (0.43) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL14878464 | 0.72 | MMP9 (0.43) | MMP1MMP3MMP7MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |