Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP13 | P45452 | 7/20 | 0.43 |
| ▸ | MMP1 | P03956 | 7/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | MMP7 | P09237 | 5/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878466 | 0.94 | MMP1 (0.44) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL12905350 | 0.92 | MMP9 (0.42) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL778946 | 0.91 | MMP1 (0.55) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL14878435 | 0.90 | MMP9 (0.42) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL14878465 | 0.90 | MMP9 (0.41) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL12905352 | 0.85 | MMP1 (0.43) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL778778 | 0.84 | MMP1 (0.56) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL328467 | 0.84 | MMP1 (0.50) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL14878456 | 0.83 | MMP1 (0.43) | MMP9MMP13MMP1MMP3MMP7 | |
| SCHEMBL12905331 | 0.82 | MMP9 (0.41) | MMP9MMP13MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |