Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057615 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRKIF11CNR2MEN1 | |
| SCHEMBL12057614 | 0.85 | LMNA (0.60) | ALDH1A1TSHRKIF11MAPTKDM4E | |
| SCHEMBL12057619 | 0.85 | LMNA (0.53) | ALDH1A1TSHRKIF11CNR2KMT2A | |
| SCHEMBL12057612 | 0.85 | LMNA (0.53) | ALDH1A1TSHRKIF11CNR2KMT2A | |
| SCHEMBL12057642 | 0.83 | KIF11 (0.52) | ALDH1A1TSHRKIF11CNR2MEN1 | |
| SCHEMBL12057640 | 0.83 | KIF11 (0.52) | ALDH1A1TSHRKIF11CNR2MEN1 | |
| SCHEMBL12057613 | 0.83 | L3MBTL1 (0.54) | ALDH1A1TSHRKIF11MAPTKDM4E | |
| SCHEMBL12057616 | 0.82 | TNNI3 (0.65) | ALDH1A1TSHRKIF11CNR2MEN1 | |
| SCHEMBL12057641 | 0.82 | KIF11 (0.48) | ALDH1A1TSHRKIF11CNR2MEN1 | |
| SCHEMBL21597132 | 0.81 | FLT3 (0.67) | ALDH1A1TSHRKIF11CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583963-A1 | Proline analogs as ligands for cannabinoid receptors for the treatment of pain | Purdue Pharma L.P. (US) | 2013-04-24 | — | — | EP | disclosed |