Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580853 | 0.85 | KMT2A (0.61) | KMT2ANPSR1MEN1MAPTRAB9A | |
| SCHEMBL17662852 | 0.85 | KMT2A (0.61) | HDAC8KMT2ANPSR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL20166696 | 0.83 | KMT2A (0.59) | KMT2ANPSR1MEN1MAPTRAB9A | |
| SCHEMBL19605409 | 0.83 | HDAC8 (0.63) | HDAC8KMT2AMEN1RAB9ALMNA | |
| SCHEMBL14881985 | 0.81 | HDAC8 (0.64) | HDAC8HDAC6HDAC1SMPD1KDM4E | |
| SCHEMBL17064043 | 0.81 | RAB9A (0.50) | ALOX15GFERADAM17HDAC8KMT2A | |
| SCHEMBL13753982 | 0.81 | POLB (0.58) | KMT2ANPSR1MEN1MAPTRAB9A | |
| SCHEMBL30744738 | 0.80 | MRGPRX4 (0.63) | KMT2ANPSR1MEN1MAPTRAB9A | |
| SCHEMBL1965898 | 0.80 | MRGPRX4 (0.63) | KMT2ANPSR1MEN1MAPTRAB9A | |
| SCHEMBL30744976 | 0.79 | LMNA (0.56) | KMT2ANPSR1MEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |