Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887278 | 0.87 | DYRK1A (0.46) | MAPTNPC1RAB9ASMN1; SMN2GCGR | |
| SCHEMBL11973162 | 0.82 | NOTUM (0.39) | NOTUMMAPTMEN1KMT2ACCNB2 | |
| SCHEMBL3177261 | 0.72 | MAP4K4 (0.47) | KMOMAP4K4RAB9A | |
| SCHEMBL22261807 | 0.69 | CCNB2 (0.37) | NOTUMMAPTMEN1KMT2ACCNB2 | |
| SCHEMBL435455 | 0.68 | CYP1A2 (0.38) | NOTUMMAPTKMT2APOLBPTPN11 | |
| SCHEMBL8637231 | 0.68 | DPP4 (0.41) | MAPTMEN1KMT2AAHRPOLB | |
| SCHEMBL9538592 | 0.65 | CYP2A6 (0.50) | MAPTMEN1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL4600920 | 0.65 | GCGR (0.42) | NOTUMPOLBPTPN11NPC1RAB9A | |
| SCHEMBL3499564 | 0.65 | DYRK1A (0.59) | MEN1KMT2AMAP4K4CYP1A2KDM4E | |
| SCHEMBL29432634 | 0.65 | DYRK1A (0.59) | MEN1KMT2AMAP4K4CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |