Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14883357 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL14876942 | 0.73 | MEN1 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL2595128 | 0.73 | MEN1 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL2595132 | 0.73 | MEN1 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177500 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL14426564 | 0.72 | PSMB8 (0.92) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL1806941 | 0.61 | TSHR (0.60) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL13898512 | 0.61 | TSHR (0.60) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7534587 | 0.61 | TSHR (0.52) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL31702246 | 0.61 | TRPA1 (0.86) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | KDR, REN, FLT1 | ALDH1A1 1466/4885MEN1 2094/4885KMT2A 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.