Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RAC2 | P15153 | 1/20 | 0.31 |
| ▸ | RAC3 | P60763 | 1/20 | 0.31 |
| ▸ | CDC42 | P60953 | 1/20 | 0.31 |
| ▸ | RAC1 | P63000 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14886351 | 1.00 | TSPO (0.34) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL16076433 | 0.99 | KDM4E (0.33) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL14886240 | 0.98 | KDM4E (0.37) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL14886343 | 0.98 | PDK2 (0.32) | TSPOPDK2 | |
| SCHEMBL14886329 | 0.98 | PDK2 (0.32) | TSPOPDK2 | |
| SCHEMBL14886238 | 0.97 | KDM4E (0.33) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL14886337 | 0.97 | KDM4E (0.33) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL14886302 | 0.97 | KDM4E (0.33) | TSPOKDM4EATML3MBTL1HDAC4 | |
| SCHEMBL16076389 | 0.97 | KDM4E (0.32) | KDM4EATML3MBTL1 | |
| SCHEMBL14886395 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978957-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| US-9978957-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| EP-2768808-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-15 | — | — | EP | disclosed |
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9515266-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9515266-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20140275530-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275530-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| WO-2013056776-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EFNA1, TTI1, TERT | TSPO 406/4885KDM4E 2652/4885ATM 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.